The 23-year-old Garland, who was skipped in the roation and last pitched on May 8 against the A's (five runs in five innings), threw six innings, allowing two runs (one earned) on six hits and a walk. Garland struck out two and threw 95 pitches.
Garland's outing wasn't good enough, however, to match Mays, who is 8-2 lifetime with a 3.23 ERA in 16 games (15 starts, 100 1/3 innings) against the Sox. Mays gave up one run in 6 2/3 innings against a Sox offense, which ranks 12th in the AL in both runs (171) and batting average (.249).
The Twins took the lead early, a lead they never gave up, on a Corey Koskie single to right field. Cristian Guzman held up at third on the throw home by Armando Rios, but the ball short-hopped and bounced off the chest of Miguel Olivo and down the first base line, allowing Guzman to score.
Rios was playing right field in a suprise move that had Magglio Ordonez in center for the injured Willie Harris. Ordonez wasn't sure why he was there, but all signs look at the .187 batting average Sox' centerfielders have held, and the recently started rumors of Garland being on the block in hopes of getting another bat in a struggling offense.
Garland kept the Twins off the board up until the fourth when Dustin Mohr grounded out, scoring Bobby Kielty from third. Garland was pulled after the sixth for Tom Gordon.
After Gordon's scoreless sixth, Kelly Wunsch, down 2-1, gave up a run off a Koskie sacrifice fly. In the inning, Wunsch made a throwing error on a Guzman sacrifice bunt attempt, putting both him and Jacque Jones in scoring position. Billy Koch relieved Wunsch to get the final out.
The Sox scored their only run in the seventh on a Miguel Olivo single. The Sox loaded the bases with two outs, forcing Mays out of the game, but after Olivo's single, D'Angelo Jimenez flied out to end the inning.
In the inning, Carlos Lee seemed to of had a two-run homer to center, but Torii Hunter climbed the wall to make the catch. J.C. Romero and Latroy Hawkins each threw 2/3 of an inning in relief and Eddie Guardado threw a 1-2-3 ninth for his ninth save.
Lee went 2-4 with two infield singles, Jimenez and Paul Konerko both went 1-4 with a single, Ordonez went 1-4 with an infield single and Joe Crede and Olivo went 1-3 each. The Sox had no hit further than a single.
The Sox will hope to prevent a sweep and win game three of the set on Sunday afternoon at 1:05 CT with Estaban Loaiza going up against Kyle Lohse. The game will be televised on Fox Sports Net Chicago.