Two batters later -- after Kelly Wunsch relieved Tom Gordon, getting Bobby Higginson to groundout -- Dmitri Young hit a double to left over the head of Carlos Lee, who misjudged it off the bat. Santiago scored, giving the Tigers a 3-2 lead. The White Sox are now 3-18 when they make an error.
The Sox had a 2-1 lead after five innings, scoring on a Magglio Ordonez RBI-double in the first and Crede's third homer of the season in the fifth. In the sixth inning, Higginson doubled, advanced to third on a sacrifice fly to center and scored on a Carlos Pena sacrifice fly, tying the game. Detroit scored their first run with an Eugene Kingsale RBI-single in the fifth.
Chris Spurling relieved Maroth after seven innings, earning his second save of the season.
Gordon threw 1 2/3 scoreless innings (1 unearned run), Wunsch threw 2/3 of an inning and Gary Glover threw a scoreless ninth inning.
Garland walked three and struck out two on 85 pitches. He lowered his ERA to 5.70.
Lee, Paul Konerko and Jose Valentin each went 0-4, while Frank Thomas went 0-3 with two strikeouts. Miguel Olivo went 1-3 with a single and threw out a base-stealer. The Sox grounded into three double plays in the game and now have a league-leading 46 on the season.
Game two of the series will be on Saturday at 6:05 p.m. CT and will be televised on Fox Sports Net Chicago. Esteban Loaiza is scheduled to start against Gary Knotts.