Loaiza, who improved his record to 9-2 with the win, pitched seven innings, giving up three runs on seven hits (two homers). Loaiza struck out nine and threw 100 pitches.
Loaiza gave up two of the three runs in the first two innings on a Shawn Green home run and Paul Lo Duca inside-the-park homer, which was initially charged as a double and two-base error on Magglio Ordonez. Lo Duca hit the ball down the right field line, off the field-box facade, leaving little time for Ordonez to recover.
Dodgers' starter Odalis Perez kept the Sox hit-less until the fourth inning, when four straight singles by D'Angelo Jimenez, Tony Graffanino, Frank Thomas and Ordonez scored a run while loading the bases. Carlos Lee then grounded into a double play, scoring the tying run.
Tied 2-2, the Sox ran away in the fifth with five runs, two coming from a Thomas homer. A Jimenez groundout scored the go-ahead run and a Graffanino double scored two.
Loaiza gave up an RBI-single to David Roberts in the Dodgers half of the fifth, and left two innings later, being replaced by Damaso Marte and Billy Koch, who each threw a scoreless inning.
The Sox put the final runs up in the seventh on Lee's 10th homer of the year, a three-run shot, putting the Sox up 10-3. Lee went 2-5.
Graffanino, playing short in place of Jose Valentin, went 3-5 with three runs scored and two RBIs, while Thomas went 2-3, raising his batting average to .288, the highest it has been since April 2.
The Sox have Monday off and will start a three-game set against the San Francisco Giants on Tuesday at 7:05 p.m. CT, with Jon Garland going up against Jason Williams. The game will be televised on WCIU.