Colon didn't last long at all, throwing his shortest outing (3 2/3 innings) since October 4, 2001, when he lasted just 1 1/3 innings versus the Royals.
Two runs came on a Dmitri Young homer in a 43-pitch first, while another two came in the fourth, leading to Colon getting pulled in favor of lefty Dave Sanders with two men on and two outs. Colon gave up five runs total and threw 104 pitches.
Sanders pitched out of Colon's jam, but couldn't get himself out of his own in the fifth as the Tigers expanded their lead to 9-1 with four runs.
Rick White relieved Sanders, ended the inning, and threw 2 1/3 scoreless innings total. Billy Koch threw two innings, giving up the eventual game-winning run as the Sox scored scored three runs in the seventh and four in the ninth.
The three-run seventh all came from a homer by Miguel Olivo, his sixth of the year, while two more homers -- a three-run shot by Carlos Lee and solo homer by Carl Everett -- did the scoring in the ninth off Tigers' closer Chris Mears. Lefty starter Mike Maroth, who won just his fifth game, gave up five runs in 6 1/3 innings.
Only one of the Sox' nine runs came off a hit other than a homer, a RBI-single by Ordonez in the sixth. The White Sox first run came off a solo homer by Joe Crede. For Crede, it was his ninth homer and 39th RBI.
Crede, along with Everett, Tony Graffanino and Roberto Alomar, had two hits in the game. Every Sox hitter had at least one hit in the game, giving them 13 total.
Game two of the series will be played Friday night at 7:05 CT, with Mark Buehrle going up against Matt Roney. It will be televised on WCIU.